NK Immunorestoration of Cancer Patients by MGN-3, A Modified Arabinoxylan Rice Bran (Study of 32 Patients Followed for up to 4 Years)
M.Ghoneum and J.Brown2000 NK cells have been characterized as non-B cells or non-T cells lacking the characteristics of mature macrophages which develop from the bone marrow independently of thymic influence. NK cells play a crucial role in tumor rejection, immune surveillance, resistance to infections, and immune regulation. NK cell destruction of cancer cells involves a sequence […]
Production of tumor necrosis factor-alpha and interferon-gamma from human peripheral blood lymphocytes by MGN-3, a modified arabinoxylan from rice bran, and its synergy with interleukin-2 in vitro
Ghoneum M, Jewett A.2000 Recently, we presented evidence for the role of MGN-3, an enzymatically modified arabinoxylan extracted from rice bran, in potent activation of human natural killer (NK) cell function in vivo and in vitro. In the current study, we examined the mechanism by which MGN-3 elevated NK cytotoxic activity. We did this by […]
Scavenging Activity of MGN-3 (Arabinoxylane from Rice Bran) with Natural Killer Cell Activity on Free Radicals
Kenji Tazawa, Hirohide Namikawa, Naoko Oida, Kayoko ltoh, Miki Yatsuzuka, Jun Koike, Masahiro Masada and Hiroaki Maeda2000 MGN-3, which produces a remarkable increase in natural killer cell activity, showed a high scavenging rate on hypoxanthine-xanthine oxidase generated superoxide anion radicals, and on ferrous sulfate-hydrogen peroxide and UV light reaction system generated hydroxyl radicals. The S-group […]